Journal article · Integrative Biology 2016
Mathematical Modelling of Microtumour Infiltration Based on In Vitro Experiments
Integrative Biology, 2016
Abstract
The objective of this study was to build a mathematical model able to describe the growth and the real invasion pattern of multicellular tumour spheroids immersed in a collagen matrix. The model may be used in a descriptive (case-specific) as well as in a predictive (population-dependent) way, depending on the type of the input parameters (a shape function obtained from a given experimental case or an aleatory shape function generated by data mining and Monte Carlo tools from the entire dataset, respectively).
This kind of empirical-numerical interaction has wide application potential at the basic research and at the clinical level.
The version of record is at doi:10.1039/c6ib00110f.
Cite this paper
Download .bib ↓Emmanuel Lujan, Liliana N. Guerra, Alejandro Soba, Nicolás Visacovsky, Daniel Gandía, Juan Carlos Calvo and Cecilia Ana Suárez, “Mathematical Modelling of Microtumour Infiltration Based on In Vitro Experiments,” Integrative Biology, 2016.
doi:10.1039/c6ib00110f
@article{lujan2016mathematical,
title={Mathematical Modelling of Microtumour Infiltration Based on In Vitro Experiments},
author={Luj{\'{a}}n, Emmanuel and Guerra, Liliana N. and Soba, Alejandro and Visacovsky, Nicol{\'{a}}s and Gand{\'{i}}a, Daniel and Calvo, Juan Carlos and Su{\'{a}}rez, Cecilia Ana},
journal={Integrative Biology},
year={2016},
doi={10.1039/c6ib00110f}
}