Conference paper · 1st World Congress on Electroporation and… 2016
Electrolytic Ablation Dose Planning Methodology
1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Springer, 2016
Abstract
Electrolytic ablation (EA), a medical treatment increasingly used in solid tumor ablation, consists in the passage of a low direct electric current through two or more electrodes inserted in the tissue thus inducing pH fronts that destroys the tumor. The combined use of EA with a recently introduced one-probe two electrode device (OPTED) results in a minimally invasive tissue ablation technique.
Despite its success related to low cost and minimum side effects, EA has drawbacks such as the difficulty in determining the current and time needed to assure total tumor ablation while avoiding healthy tissue intrusion. Here we introduce a realistic dose planning methodology in terms of the coulomb dosage administered and the associated pH tracking, that predicts an optimal EA/OPTED protocol treatment for a given tumor size.
The version of record is at doi:10.1007/978-981-287-817-5_23.
Cite this paper
Download .bib ↓Emmanuel Lujan, Herman Schinca, Nahuel Olaiz, Santiago Urquiza, Fernando Víctor Molina, Pablo Turjanski and Guillermo Marshall, “Electrolytic Ablation Dose Planning Methodology,” 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Springer, 2016.
doi:10.1007/978-981-287-817-5_23
@inproceedings{lujan2016electrolytic,
title={Electrolytic Ablation Dose Planning Methodology},
author={Luj{\'{a}}n, Emmanuel and Schinca, Herman and Olaiz, Nahuel and Urquiza, Santiago and Molina, Fernando V{\'{i}}ctor and Turjanski, Pablo and Marshall, Guillermo},
booktitle={1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food \& Environmental Technologies},
pages={101--104},
year={2016},
organization={Springer Singapore},
doi={10.1007/978-981-287-817-5_23}
}